Washington, Sep 10 - The US Wednesday said its relationship with India was undergoing 'seismic changes' and will get a major boost during Prime Minister Manmohan Singh's visit in November.

Washington also asked Pakistan to prosecute those responsible for the Mumbai terror attacks and stop infiltration of militants into India to rebuild confidence with New Delhi.

The bilateral trade between the two countries, which currently languishes at $2.1 billion, help a huge potential of deepening their relationship, Assistant Secretary of State for South Asia Robert O. Blake said at Johns Hopkins University here.

Describing the India-American relationship as undergoing 'seismic changes', Blake said: 'Our bilateral dialogue is less and less about resolving old legacy issues that divided us such as non-proliferation, and more and more about seizing new opportunities, both bilateral and multilateral.'

He said the US was committed to deepening its relationship with India on five pillars - strategic cooperation; collaboration in science, technology and health; energy and climate change; education and trade and agriculture.

Blake said the strategic partnership between the two countries got a major boost during Secretary of State Hillary Clinton's visit to India in July.