'I want to be in a good position this summer going into the Open.'
The 42nd-ranked Wimbledon quarter-finalist against Roddick said it required an adjustment from grass onto a hard court.
'It always takes a couple of matches to get into rhythm,' Hewitt said.
'This is a quality field, and it would be tough to win. But I have the chance to go into the Masters events at Montreal and Cincinnati (Ohio) in good form with a decent showing here.'
Elsewhere in the second round, Chilean fourth seed Fernando Gonzalez started with a defeat of Colombian Alejandro Falla 7-5, 7-5, while last week's Croatian finalist Juan Carlos Ferrero upset fellow seventh-seeded Spaniard Tommy Robredo 6-3, 6-2.
German Philipp Petzschner mounted a comeback to dispatch ninth-seeded Mardy Fish 1-6, 6-4, 6-1 after the American had complained last week of abdominal muscle pain in Los Angeles.
Croatian Ivo Karlovic struck 18 aces to defeat German veteran Rainer Schuettler 6-4, 7-5, while Frenchman Marc Gicquel advanced after just three games and 16 minutes when Serb Viktor Troicki retired injured trailing 3-0.