Environment and Parliamentary Affairs Minister Sailen Sarkar was relieved of the parliamentary affair ministry.
Law and Justice Minister Rabi Lal Moitra will now also be in charge of parliamentary affairs.
The functioning of the panchayat, health and power ministries had drawn flak from within the party and also in Left Front circles as the ruling combine suffered back-to-back losses in panchayat, Lok Sabha, municipal polls as also assembly by-polls over the last 14 months.
Bandopadhyay and Sarkar are ailing, while Mishra was seemingly overburdened with the load of the key panchayat and health departments.