Washington, Sep 15 (DPA) Iran will be presented with a stark choice of either abandoning its nuclear ambitions or facing increased isolation in the international community when it meets with the world's major powers, the US State Department said Monday.

The US reaction came after it was announced that Iran will meet with officials from the five UN Security Council members - the US, China, Russia, Britain and France - plus Germany Oc 1 to discuss its disputed nuclear programme.

It will be the first such meeting between Iranian officials and The six countries since July 2008. State Department spokesman Ian Kelly said the nuclear issue would be 'front-and-center' in the talks, despite Iran's insistence that it considers the matter closed.

'We plan to address this issue of (Iran) not living up to their obligation head on,' Kelly told reporters in Washington.