New Delhi, Sep 17 - India is working overtime to come out with a swine flu vaccine and will soon produce the raw material used in the anti-flu drug, the government said Thursday as eight more people died of the influenza A (H1N1) virus, taking the toll to 220.

Union Health Minister Ghulam Nabi Azad said 'India is taking prompt and proactive measures to delay and limit the spread of the diseases and also to build capacity to mitigate the impact of the pandemic.'

He said India was among the first few countries to stake claim to produce the vaccine.

'Three companies - Serum Institute, Panaxea Bio-Tech and Bhatat Biotech are working on this and the government has given Rs.100 million each to these institutes,' he told reporters here.

'The vaccine is likely to be available by April next year,' he added.

He said the ministry is also in touch with multinational companies working on producing the swine flu vaccine. 'We are in touch with them and will import the vaccine if they prepare it first,' he added.

Azad said presently there are 53 laboratories - 31 government and 22 private - that are conducting the H1N1 tests, as compared to two when the flu was first reported in India on May 16.

Of these, 34 labs - 22 government and 12 private - are operational.

The government has also increased its medicine stockpile with 10 million Oseltamivir capsules, one of the anti-influenza drugs, to 40 million capsules, and 450,000 bottles of Oseltamivir syrup.

'We have also permitted regulated sale and distribution of Oseltamivir and Zanamivir. Both these drugs will be available in retail markets against proper medical prescription from chemists having a license,' he said.

He said India will soon produce raw material for Oseltamivir, one of the drugs used in treatment of Influenza A (H1N1) virus. This will help bring down the cost of the drug.

'We have decided to allow indigenous production of shikimic acid,' Azad said.

Shikimic acid, a white crystalline compound of nonnitrogenous acid found in various plants naturally, is needed to produce Oseltamivir.